Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 444
interventional 386
Observational 57
Registry 1

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 289
Drug|placebo 47
Drug|Other 11
Device 9
Procedure 7
Drug|Procedure 5
Device|Other 4
Device|Drug 3
Other 3
Combination Product|Drug 2
Drug|Other|placebo 2
Combination Product 1
Device|placebo 1
Device|Procedure 1
Diagnostic Test 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 183
NA 64
Japan 17
Canada 12
China 12
France 6
United Kingdom 6
Austria 5
Spain 5
Greece 4
Korea, Republic of 4
United States|Canada 4
Brazil 3
Finland 3
Germany 3
Italy 3
Hungary 2
India 2
Switzerland 2
Argentina 1
Armenia 1
Australia 1
Australia|Belgium|Denmark|France|Germany|Greece|Ireland|Italy|Netherlands|Spain|Sweden|United Kingdom 1
Australia|Czechia|France|Greece|Pakistan|Portugal|Thailand|United Kingdom 1
Austria|Belgium|Czechia|France|Germany|Hungary|Italy|Latvia|Poland|Spain|United Kingdom 1
Austria|Belgium|Italy|Portugal|Switzerland|United Kingdom 1
Belgium 1
Bulgaria|Israel 1
Canada|Slovenia 1
Colombia|Mexico 1
Denmark|Finland|Norway|Sweden 1
Estonia 1
Estonia|Germany|Spain 1
Finland|Germany 1
Finland|Sweden 1
France|Germany|Greece|Italy|Sweden 1
Germany|Belgium|Czechia|France|Hungary|Israel|Italy|Poland|Spain|United Kingdom 1
Greece|Italy 1
Iran, Islamic Republic of 1
Israel|Italy|United Kingdom 1
Latvia 1
Malaysia 1
Mexico 1
Panama 1
Poland 1
Singapore 1
Sweden 1
Taiwan 1
United States|Argentina|Austria|Belgium|Brazil|Canada|Colombia|Czechia|Denmark|Egypt|France|Germany|Hong Kong|Israel|Italy|Korea, Republic of|New Zealand|Peru|Philippines|Poland|Russian Federation|Singapore|South Africa|Spain|Turkey|United Kingdom 1
United States|Argentina|Canada|Colombia|Czechia|Egypt|Germany|Italy|Korea, Republic of|Malaysia|New Zealand|Singapore|South Africa|Turkey|United Kingdom 1
United States|Australia 1
United States|Australia|Austria|Belgium|Brazil|Denmark|Hong Kong|Hungary|Israel|Peru|Philippines|Poland|Spain|Taiwan 1
United States|Australia|Belgium|Brazil|Canada|Germany|Israel|Philippines|Singapore|Spain 1
United States|Australia|Canada|Denmark|Estonia|Germany|Israel|New Zealand|Philippines|Poland|Russian Federation|United Kingdom 1
United States|Australia|Czech Republic|Germany|Hungary|Israel|Russian Federation|Spain|United Kingdom 1
United States|Austria|Canada|Germany 1
United States|Belgium|Denmark|France|Italy|Poland|Russian Federation|Singapore|Spain|Thailand 1
United States|Bulgaria|Czech Republic|Hungary 1
United States|Bulgaria|Czechia|Denmark|France|Germany|Hungary|Ireland|Italy|Poland|South Africa|Sweden|United Kingdom 1
United States|Denmark|Italy|Portugal|South Africa|Spain 1
United States|Estonia|Germany|Spain 1
United States|Japan 1
United States|Singapore 1
United States|Sweden|United Kingdom 1
United States|United Kingdom 1

Sites per Study

Site_count Study_Count
1 265
2 21
3 6
4 3
5 11
6 3
7 3
8 6
9 5
10 6
11 4
12 3
13 4
14 3
15 2
17 2
18 2
19 1
21 4
22 3
23 1
25 3
27 1
29 1
31 1
34 1
37 1
40 2
47 1
48 1
50 1
53 1
54 1
55 1
57 1
58 1
64 1
67 1
74 1
98 1
102 1
106 1
113 2
134 1
176 1

Phase

Phase Study_Count
Phase 3 127
Phase 2 92
Phase 4 91
N/A 33
Phase 1 22
Phase 1/Phase 2 18
Phase 2/Phase 3 3

Number of Arms

Number_of_Arms Count_of_Studies
1 56
2 165
3 57
4 28
5 13
6 12
8 2
14 1
NA 52

Enrollment Metrics by Phase

Measure N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 9.00000 9.00000 6.0000 5.0000 201.0000 25.0000 15.0000
1st Qu. 21.00000 20.25000 54.2500 63.7500 227.0000 175.7500 48.5000
Median 50.00000 31.00000 88.5000 100.5000 253.0000 375.5000 104.0000
Mean 89.69697 40.27273 132.1111 124.2955 338.3333 405.3305 175.3103
3rd Qu. 100.00000 55.50000 156.7500 163.5000 407.0000 547.7500 224.5000
Max. 400.00000 91.00000 637.0000 656.0000 561.0000 1636.0000 1137.0000

Trial Group Type

group_type Group_Count
Experimental 478
Active Comparator 259
Placebo Comparator 57
NA 52
Other 33
No Intervention 5
Sham Comparator 4

Intervention Model

intervention_model Study_Count
Parallel Assignment 281
Single Group Assignment 71
Crossover Assignment 28
NA 3
Sequential Assignment 2
Factorial Assignment 1

Primary Purpose

primary_purpose Study_Count
Treatment 352
NA 7
Diagnostic 6
Other 6
Basic Science 5
Prevention 5
Health Services Research 2
Supportive Care 2
Screening 1

Observational Studies

Studies by Country

Country Study_Count
United States 16
Germany 6
NA 5
Canada 3
Spain 3
Switzerland 3
Austria 2
Korea, Republic of 2
Netherlands 2
Turkey 2
United Kingdom 2
Belgium 1
Belgium|Colombia|Czechia|Denmark|France|Germany|Greece|Italy|Peru|Portugal|Slovakia|Spain|Sweden|United Kingdom 1
Egypt 1
Egypt|Saudi Arabia|United Arab Emirates 1
France|Italy|Netherlands|United Kingdom 1
Germany|Netherlands 1
Greece 1
Mexico 1
Slovakia 1
Taiwan 1
Thailand 1

Sites per Study

Site_count Study_Count
1 50
2 1
3 1
4 2
21 1
29 1
39 1

Enrollment Metrics

Measure Observational
Min 20.000
1st Qu 95.000
Median 200.000
Mean 1344.655
3rd Qu 964.500
Max 28812.000

Observation Model

observational_model Study_Count
Cohort 29
Case-Only 15
NA 7
Case-Control 2
Case-Crossover 2
Case Control 2

Time Perspective

time_perspective Study_Count
Prospective 46
Retrospective 5
NA 4
Cross-Sectional 1
Other 1

Registries

Studies by Country

Country Study_Count
Poland 1

Sites per Study

Site_count Study_Count
1 1

Enrollment Metrics

Measure Registries
Min 150
1st Qu 150
Median 150
Mean 150
3rd Qu 150
Max 150

Registry Model

observational_model Study_Count
Case-Control 1

Time Perspective

time_perspective Study_Count
Prospective 1

Follow-up

target_duration Study_Count
10 Years 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT03750201 A Study to Assess an Automated Laser Device for Direct Selective Laser Trabeculoplasty https://ClinicalTrials.gov/show/NCT03750201 Recruiting Belkin Laser Ltd. 2022-04-30
NCT03395535 Laser-1st vs Drops-1st for Glaucoma and Ocular Hypertension https://ClinicalTrials.gov/show/NCT03395535 Completed Moorfields Eye Hospital NHS Foundation Trust 2017-12-25
NCT03657797 Phase 2 Dose-Response Study Evaluating the Safety and Efficacy of NCX 470 vs Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT03657797 Completed Nicox Ophthalmics, Inc. 2019-08-23
NCT03825380 Efficacy and Safety Assessment of T4032 Versus Lumigan® in Ocular Hypertensive or Glaucomatous Patients https://ClinicalTrials.gov/show/NCT03825380 Recruiting Laboratoires Thea 2020-04-30
NCT03822559 A Study of DE-111A on the Treatment of Open Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT03822559 Recruiting Santen Pharmaceutical Co., Ltd. 2022-03-31
NCT03310580 Study of Netarsudil Ophthalmic Solution in Japanese/Japanese-American Subjects With Open-angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT03310580 Completed Aerie Pharmaceuticals 2018-10-25
NCT03293992 A Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7058584 Following 7 Days of Instillation of Eye Drops in Patients With Primary Open Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT03293992 Completed Hoffmann-La Roche 2017-12-15
NCT03284853 Safety and Efficacy Study of PG324 (Netarsudil/Latanoprost 0.02% / 0.005%) Ophthalmic Solution Compared to GANFORT® Ophthalmic Solution in Open Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT03284853 Active, not recruiting Aerie Pharmaceuticals 2020-12-31
NCT03257813 Non-inferiority of PRO-122 Ophthalmic Solution vs KRYTANTEK Ofteno® in Glaucoma or Ocular Hypertension (CONFORTK) https://ClinicalTrials.gov/show/NCT03257813 Completed Laboratorios Sophia S.A de C.V. 2017-03-01
NCT03233308 Study of Netarsudil Ophthalmic Solution in Subjects With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT) https://ClinicalTrials.gov/show/NCT03233308 Completed Aerie Pharmaceuticals 2018-04-19
NCT03216902 A Phase IIb Safety and Efficacy Study of DE-126 Ophthalmic Solution in Primary Open-Angle Glaucoma or Ocular Hypertension- Angel Study https://ClinicalTrials.gov/show/NCT03216902 Completed Santen Inc. 2018-02-27
NCT03204487 A Study on the Effect of Changing From Preserved Prostaglandin Formulations to Preservative Free Tafluprost on Tear Film Thickness https://ClinicalTrials.gov/show/NCT03204487 Completed Ordination Dr. Hommer 2017-04-25
NCT03201354 Efficacy and Safety of the ExPRESS Implant Versus Deep Sclerectomy in Combined Surgery https://ClinicalTrials.gov/show/NCT03201354 Completed Institut Catala de Retina 2015-06-30
NCT03192826 Brinzolamide/Brimonidine Combination vs Brimonidine 0.2% in the Prevention of IOP Rise After Nd-YAG Laser Capsulotomy https://ClinicalTrials.gov/show/NCT03192826 Completed University Hospital of Patras 2017-07-08
NCT03187418 Treatment Outcomes of MicroPulse Trans-scleral Cyclophotocoagulation in Uncontrolled Glaucoma https://ClinicalTrials.gov/show/NCT03187418 Active, not recruiting Centre hospitalier de l’Université de Montréal (CHUM) 2019-02-28
NCT03131167 Study of SHP639 Eye Drops in Adults With High Eye Pressure or Primary Open-angle Glaucoma https://ClinicalTrials.gov/show/NCT03131167 Completed Shire 2018-05-30
NCT02993445 Effect of Alternate Therapies on Intraocular Pressure in Ocular Hypertension https://ClinicalTrials.gov/show/NCT02993445 Completed Temple University 2016-02-29
NCT02989909 Clinical Evaluation of CATS Tonometer Prism https://ClinicalTrials.gov/show/NCT02989909 Completed Intuor Technologies, Inc. 2017-11-30
NCT02981446 A Phase III Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution Compared With Latanoprost Ophthalmic Solution in Subjects With OAG or OHT https://ClinicalTrials.gov/show/NCT02981446 Completed Santen Pharmaceutical Co., Ltd. 2019-01-31
NCT02967614 KJ-TFC-004 Drug-drug Interaction Study https://ClinicalTrials.gov/show/NCT02967614 Completed Kukje Pharma 2017-12-31
NCT02874846 Nocturnal/Diurnal Intraocular Pressure-Lowering Effect of Netarsudil Ophthalmic Solution https://ClinicalTrials.gov/show/NCT02874846 Completed Aerie Pharmaceuticals 2016-09-30
NCT02858284 Evaluation of Safety and Efficacy of TUG (Therapeutic Ultrasound for Glaucoma) in the Treatment of Primary Open Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT02858284 Completed EyeSonix 2018-08-22
NCT02829996 Study of Fixed-Dose Combinations of Trabodenoson and Latanoprost in Adults With OHT or POAG https://ClinicalTrials.gov/show/NCT02829996 Completed Inotek Pharmaceuticals Corporation 2017-05-24
NCT02822742 A Study Assessing the Safety and Efficacy of DE-117 in Subjects With POAG or OH Who Are Non-/Low-responders to Latanoprost: FUJI Study https://ClinicalTrials.gov/show/NCT02822742 Completed Santen Pharmaceutical Co., Ltd. 2017-04-28
NCT02822729 A Long-term Study of DE-117 Ophthalmic Solution Monotherapy and Concomitant Use of DE-117 Ophthalmic Solution With Timolol Ophthalmic Solution in Patients With OAG or OH: RENGE Study https://ClinicalTrials.gov/show/NCT02822729 Completed Santen Pharmaceutical Co., Ltd. 2017-11-09
NCT04442464 Intraocular Pressure in Ocular Hypertensives With Scleral Lens Wear https://ClinicalTrials.gov/show/NCT04442464 Recruiting Mayo Clinic 2021-12-31
NCT02754570 The Diurnal and Nocturnal Effect of Pilocarpine on Intraocular Pressure and Ocular Perfusion Pressure https://ClinicalTrials.gov/show/NCT02754570 Completed University of Colorado, Denver 2017-12-31
NCT02743780 A Three Part Study of MGV354 in Ocular Hypertension or Glaucoma https://ClinicalTrials.gov/show/NCT02743780 Completed Alcon Research 2016-09-20
NCT02742649 A Study to Evaluate Efficacy and Safety of a Fixed Combination Ocular Insert in Participants With Open-angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT02742649 Completed ForSight Vision5, Inc. 2016-12-31
NCT02710916 SD-OCT Multimodal Analysis in GLaucoma https://ClinicalTrials.gov/show/NCT02710916 Completed University Hospital, Bordeaux 2018-12-21
NCT02674854 Double-masked Study of PG324 Ophthalmic Solution in Patients With Open-angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT02674854 Completed Aerie Pharmaceuticals 2017-03-31
NCT02623738 A Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension -AYAME Study- https://ClinicalTrials.gov/show/NCT02623738 Completed Santen Pharmaceutical Co., Ltd. 2017-02-10
NCT02622334 A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO5093151 in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT). https://ClinicalTrials.gov/show/NCT02622334 Completed Hoffmann-La Roche 2016-07-28
NCT02617459 Levobetaxolol Hydrochloride Eye Drops for Treatment of Primary Open-angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT02617459 Recruiting Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd. 2020-12-31
NCT02585375 Latanoprost Preserved Versus Unpreserved: Effect on Tear Film Thickness as Measured With OCT https://ClinicalTrials.gov/show/NCT02585375 Recruiting Medical University of Vienna 2020-12-31
NCT02636946 A Comparison of Bimatoprost SR to Selective Laser Trabeculoplasty in Patients With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT02636946 Active, not recruiting Allergan 2021-02-28
NCT02507687 Comparison of Bimatoprost SR to Selective Laser Trabeculoplasty in Patients With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT02507687 Recruiting Allergan 2021-10-31
NCT02571712 Safety of GANFORT® Ophthalmic Solution in Chinese Patients With Open-angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT02571712 Completed Allergan 2018-06-21
NCT02565173 Study of Trabodenoson in Adults With Ocular Hypertension or Primary Open-angle Glaucoma https://ClinicalTrials.gov/show/NCT02565173 Completed Inotek Pharmaceuticals Corporation 2016-11-30
NCT02558400 Double-masked Study of PG324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT02558400 Completed Aerie Pharmaceuticals 2017-05-17
NCT02558374 Double-masked Study of Netarsudil (AR-13324) Ophthalmic Solution in Subjects With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT02558374 Completed Aerie Pharmaceuticals 2016-12-31
NCT02539758 The Effect of Ocular Massage on the Management of Elevated Intraocular Pressure After Acute Angle Closure https://ClinicalTrials.gov/show/NCT02539758 Completed Tianjin Medical University Eye Hospital 2014-09-30
NCT02537015 An Open-label Extension Study to Evaluate the Safety of the 13 mg Bimatoprost Ocular Insert https://ClinicalTrials.gov/show/NCT02537015 Completed ForSight Vision5, Inc. 2016-08-11
NCT02531152 28-Day Repeated Topical Study to Evaluate the Safety and Activity of 5 Escalating Dose Levels of SAR366234 and One Dose of Latanoprost in Patients With Open Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT02531152 Completed Sanofi 2016-04-30
NCT02512042 Bioequivalence Study With Clinical Endpoint Comparing Brinzolamide 1% Ophthalmic Suspension to Azopt® 1% Ophthalmic Suspension In the Treatment of Chronic Open Angle Glaucoma or Ocular Hypertension in Both Eyes https://ClinicalTrials.gov/show/NCT02512042 Completed Actavis Inc. 2016-04-30
NCT02466399 POLAT-001 Compared to Latanoprost Ophthalmic Solution in Patients With Ocular Hypertension and Open-angle Glaucoma https://ClinicalTrials.gov/show/NCT02466399 Completed Peregrine Ophthalmic 2016-04-30
NCT02434250 Selective Laser Trabeculoplasty After Failed Phacoemulsification With Eximer Laser Trabeculectomy https://ClinicalTrials.gov/show/NCT02434250 Completed University of Zurich 2016-10-31
NCT02419508 SIMBRINZA® Suspension BID as an Adjunctive to Prostaglandin Analogue (PGA) https://ClinicalTrials.gov/show/NCT02419508 Completed Alcon Research 2018-02-27
NCT02390245 Philadelphia Telemedicine Glaucoma Detection and Follow-Up Study https://ClinicalTrials.gov/show/NCT02390245 Active, not recruiting Wills Eye 2019-09-30
NCT02358369 Dose-Ranging Study of the Bimatoprost Ocular Insert https://ClinicalTrials.gov/show/NCT02358369 Completed ForSight Vision5, Inc. 2015-08-31
NCT02339584 Efficacy and Safety of Brinzolamide/Brimonidine Fixed Combination BID Compared to Brinzolamide BID Plus Brimonidine BID in Subjects With Open-Angle Glaucoma (OAG) or Ocular Hypertension (OHT) https://ClinicalTrials.gov/show/NCT02339584 Completed Alcon Research 2016-11-01
NCT02338362 Inhaled Corticosteroids: Effect on Intraocular Pressure in Patients With Controlled Glaucoma https://ClinicalTrials.gov/show/NCT02338362 Completed University Health Network, Toronto 2015-02-28
NCT02312544 Phase 2b Study Evaluating Safety and Efficacy of OTX-TP Compared to Timolol Drops in the Treatment of Subjects With Open Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT02312544 Completed Ocular Therapeutix, Inc. 2015-09-30
NCT02278614 Efficacy and Safety Assessment of T2347 Versus Xalacom® in Ocular Hypertensive or Glaucomatous Patients https://ClinicalTrials.gov/show/NCT02278614 Completed Laboratoires Thea 2015-11-30
NCT02250651 Safety and Efficacy of Bimatoprost Sustained-Release (SR) in Patients With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT02250651 Completed Allergan 2018-10-25
NCT02250612 SYL040012, Treatment for Open Angle Glaucoma https://ClinicalTrials.gov/show/NCT02250612 Completed Sylentis, S.A. 2015-08-31
NCT02247804 Efficacy and Safety Study of Bimatoprost Sustained-Release (SR) in Participants With Open-angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT02247804 Completed Allergan 2018-02-19
NCT02246764 Study of Netarsudil (AR-13324) Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT02246764 Completed Aerie Pharmaceuticals 2016-12-31
NCT02207621 Evaluation of Netarsudil (AR-13324) Ophthalmic Solution in Patients With Glaucoma and Ocular Hypertension https://ClinicalTrials.gov/show/NCT02207621 Completed Aerie Pharmaceuticals 2016-03-31
NCT02207491 Double-masked Study of AR-13324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT02207491 Completed Aerie Pharmaceuticals 2015-03-31
NCT02179008 Multi-center Phase II Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT02179008 Completed Santen Inc. 2015-01-31
NCT02167035 Comparison of Combigan Two Times Daily (BID) Versus Simbrinza Three Times Daily (TID) https://ClinicalTrials.gov/show/NCT02167035 Completed Cornerstone Health Care, PA 2018-03-31
NCT02157025 A More Engaging Visual Field Test to Increase Use and Reliability in Pediatrics https://ClinicalTrials.gov/show/NCT02157025 Recruiting Nova Southeastern University 2020-12-31
NCT02143843 An Open-Label Extension Study to Evaluate the Safety of the ForSight VISION5 Product https://ClinicalTrials.gov/show/NCT02143843 Completed ForSight Vision5, Inc. 2015-12-31
NCT02140060 6-Week Proof-of-Concept Study of Travoprost/Brinzolamide Ophthalmic Suspension in Subjects With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT02140060 Completed Alcon Research 2014-11-30
NCT02129673 A Phase 1/2 Multicenter, Randomized, Study to Evaluate the Safety and Efficacy of VS101 Subconjunctival Latanoprost Insert in Subjects With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT02129673 Completed ViSci Ltd. 2017-05-31
NCT02108288 Pharmacokinetic Study of OPC-1085EL Ophthalmic Solution in Healthy Male Adult Volunteers https://ClinicalTrials.gov/show/NCT02108288 Completed Otsuka Pharmaceutical Co., Ltd. 2014-05-31
NCT02105285 Efficacy and Safety Study of OPC-1085EL Ophthalmic Solution in Subjects With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT02105285 Completed Otsuka Pharmaceutical Co., Ltd. 2015-01-31
NCT02105272 Efficacy and Safety Study of OPC-1085EL Ophthalmic Solution in Subjects With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT02105272 Completed Otsuka Pharmaceutical Co., Ltd. 2015-03-31
NCT02102750 A Study to Evaluate Pharmacokinetics of Tafluprost Ophthalmic Solution (0.0015%) in Pediatric Patients With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT02102750 Completed Santen Oy 2017-05-29
NCT02097719 Efficacy and Safety Study of Bimatoprost 0.01% Alone Compared With Travoprost 0.004% and Timolol 0.5% in Subjects With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT02097719 Completed Allergan 2014-12-31
NCT02083289 A 28 Day Study of ONO-9054 Ophthalmic Solution in Subjects With Ocular Hypertension (OHT) or Open-angle Glaucoma (OAG) https://ClinicalTrials.gov/show/NCT02083289 Completed Ono Pharmaceutical Co. Ltd 2014-12-31
NCT02061683 A Study of Bimatoprost in the Treatment of Primary Open Angle Glaucoma and Ocular Hypertension https://ClinicalTrials.gov/show/NCT02061683 Completed Allergan 2011-06-24
NCT02059278 Safety and Efficacy of T-2345 Compared to Xalatan in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT02059278 Completed Nephron Pharmaceuticals Corporation 2015-01-31
NCT01318252 AL-54478 Proof of Concept Study https://ClinicalTrials.gov/show/NCT01318252 Completed Alcon Research 2011-10-31
NCT01310777 Brinzolamide/Brimonidine Twice a Day (BID) Fixed Combination (FC) vs Brinzolamide BID and Brimonidine BID in Patients With Open Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01310777 Completed Alcon Research 2013-01-31
NCT01309204 Brinzolamide/Brimonidine Twice a Day (BID) Fixed Combination (FC) vs Brinzolamide BID Plus Brimonidine BID in Patients With Open Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01309204 Completed Alcon Research 2013-01-31
NCT01306461 Tafluprost-Timolol Fixed Dose Combination Non-Inferiority Study Against Concomitant Administrations https://ClinicalTrials.gov/show/NCT01306461 Completed Santen Oy 2012-04-30
NCT01302249 AR-12286 in Combination With Latanoprost https://ClinicalTrials.gov/show/NCT01302249 Completed Aerie Pharmaceuticals 2011-12-31
NCT01298700 Long-Term Safety of Bimatoprost Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01298700 Completed Allergan 2016-12-06
NCT01298687 Divided Dose of TRAVATAN® https://ClinicalTrials.gov/show/NCT01298687 Completed Alcon Research 2011-04-30
NCT01297920 Three Month Efficacy/Safety Study With a 3-Month Safety Extension of Brinzolamide 1%/Brimonidine 0.2% vs. Brinzolamide 1% or Brimonidine 0.2% https://ClinicalTrials.gov/show/NCT01297920 Completed Alcon Research 2012-06-30
NCT01297517 Efficacy and Safety Study of Brinzolamide 1%/Brimonidine 0.2% vs. Brinzolamide 1% and Brimonidine 0.2% https://ClinicalTrials.gov/show/NCT01297517 Completed Alcon Research 2012-03-31
NCT01292460 Tafluprost-Timolol Preservative-free Fixed Dose Combination (FDC) Superiority Study Against Monotherapies https://ClinicalTrials.gov/show/NCT01292460 Completed Santen Oy 2012-09-30
NCT01291108 Safety and Efficacy of AGN-210669 Ophthalmic Solution Compared With Bimatoprost Ophthalmic Solution in Patients With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01291108 Completed Allergan 2011-10-31
NCT01279083 Safety and Efficacy Trial to Treat Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01279083 Completed Santen Inc. 2011-11-30
NCT01271686 24-hour IOP-lowering Effect of 0.01% Bimatoprost https://ClinicalTrials.gov/show/NCT01271686 Completed University of California, San Diego 2012-10-31
NCT02057575 Study Assessing Safety and Efficacy of PG324 Ophthalmic Solution in Patients With Elevated Intraocular Pressure https://ClinicalTrials.gov/show/NCT02057575 Completed Aerie Pharmaceuticals 2014-06-30
NCT02020512 A Study of 0.03% Bimatoprost in the Treatment of Primary Open Angle Glaucoma and Ocular Hypertension https://ClinicalTrials.gov/show/NCT02020512 Completed Allergan 2012-12-31
NCT02017327 Safety and Efficacy Assessment of Monoprost® in Comparison With Lumigan® 0.01 % and Lumigan® 0.03% Unit Dose https://ClinicalTrials.gov/show/NCT02017327 Completed Laboratoires Thea 2016-07-31
NCT02014142 A Phase 2 Single-Masked, Randomized Study of Latanoprost PPDS in Ocular Hypertension or Open-Angle Glaucoma https://ClinicalTrials.gov/show/NCT02014142 Completed Mati Therapeutics Inc. 2016-12-31
NCT02003391 Efficacy of Travoprost/Timolol for Uncontrolled Intraocular Pressure https://ClinicalTrials.gov/show/NCT02003391 Completed Alcon Research 2015-05-31
NCT01995136 Investigation of Intraocular Pressure (IOP) Reduction Efficacy of Travoprost Ophthalmic Solution in Patients With Normal Tension Glaucoma https://ClinicalTrials.gov/show/NCT01995136 Completed Alcon Research 2014-06-30
NCT01987323 Safety and Efficacy of Liposomal Latanoprost in Ocular Hypertension https://ClinicalTrials.gov/show/NCT01987323 Completed Singapore Eye Research Institute 2013-06-30
NCT01979913 An Open, Non-randomized Pilot Study on the Effect of Preservative Free Tafluprost (Saflutan® Augentropfen) in Patients With Ocular Hypertension or Primary Open Angle Glaucoma With an Uncontrolled Intraocular Pressure of 30 mmHg and More https://ClinicalTrials.gov/show/NCT01979913 Completed Ordination Dr. Hommer 2014-04-30
NCT01978600 Evaluation of Intraocular Pressure Using Simbrinzaâ„¢ in Patients With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01978600 Completed Alcon Research 2014-03-31
NCT01975714 Intraocular Pressure and Tolerability Study of Preservative-free Prostaglandins (Bimatoprost and Latanoprost) on Glaucoma and Ocular Hypertension: European, Multicentric, Investigator-led, Single Masked Study https://ClinicalTrials.gov/show/NCT01975714 Completed Association for Innovation and Biomedical Research on Light and Image 2015-02-28
NCT01937312 Effect of SIMBRINZA® Suspension as an Added Therapy to a Prostaglandin Analogue https://ClinicalTrials.gov/show/NCT01937312 Completed Alcon Research 2014-05-31
NCT01937299 Effect of SIMBRINZA® Suspension as an Added Therapy to TRAVATAN Z® https://ClinicalTrials.gov/show/NCT01937299 Completed Alcon Research 2014-04-30
NCT01936389 A Prospective Study to Assess the Hypotensive Efficacy of Rho-Kinase Inhibitor AR-12286 Ophthalmic Solution 0.5% and 0.7% in Patients With Exfoliation Syndrome and Ocular Hypertension or Glaucoma https://ClinicalTrials.gov/show/NCT01936389 Completed Robert Ritch, MD, LLC. 2014-10-31
NCT01917383 A Phase II Study to Evaluate the Additivity of Trabodenoson to Latanoprost in Adults With Ocular Hypertension or Primary Open-Angle Glaucoma https://ClinicalTrials.gov/show/NCT01917383 Completed Inotek Pharmaceuticals Corporation 2014-08-31
NCT01915940 Bimatoprost Ocular Insert Compared to Topical Timolol Solution in Patients With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01915940 Completed ForSight Vision5, Inc. 2014-09-30
NCT01895972 Long-Term Safety of Latanoprostene Bunod Ophthalmic Solution 0.024% in Japanese Subjects With OAG or OHT https://ClinicalTrials.gov/show/NCT01895972 Completed Bausch & Lomb Incorporated 2015-04-02
NCT01881126 An Efficacy and Safety Study of Bimatoprost 0.01% Alone Compared With Travoprost 0.004% and Timolol 0.5% in Subjects With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01881126 Completed Allergan 2014-10-31
NCT01868126 Multi-center Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01868126 Completed Santen Inc. 2013-08-31
NCT01864642 Effects of a Single OMT on Intraocular Pressure (IOP) in Ocular Hypertenive or Glaucoma Suspect Subjects https://ClinicalTrials.gov/show/NCT01864642 Completed University of Wisconsin, Madison 2014-05-31
NCT01863953 A Safety and Efficacy Study of Fixed-Combination Bimatoprost and Brimonidine in Chronic Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01863953 Completed Allergan 2013-12-31
NCT01833741 A Study of LUMIGAN® RC in the Clinical Setting https://ClinicalTrials.gov/show/NCT01833741 Completed Allergan 2011-03-31
NCT01830140 A Safety Study of Bimatoprost in Patients With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01830140 Completed Allergan 2014-05-31
NCT01789736 A Study Assessing PG286 Ophthalmic Solution, 0.5% Compared to Its Individual Components for 28 Days https://ClinicalTrials.gov/show/NCT01789736 Completed Aerie Pharmaceuticals 2013-06-30
NCT01749930 Comparing the Safety and Efficacy of BOL-303259-X Ophthalmic Solution With Timolol Maleate Ophthalmic Solution in Subjects With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01749930 Completed Bausch & Lomb Incorporated 2015-05-31
NCT01749904 Comparing Safety and Efficacy of BOL-303259-X With Timolol Maleate in Subjects With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01749904 Completed Bausch & Lomb Incorporated 2015-06-02
NCT01739244 Dose Finding Clinical Trial With SYL040012 to Evaluate the Tolerability and Effect on Intraocular Pressure in Subjects With Ocular Hypertension or Open Angle Glaucoma https://ClinicalTrials.gov/show/NCT01739244 Completed Sylentis, S.A. 2013-05-31
NCT01731002 Study Comparing the Safety and Efficacy of AR-13324 to Latanoprost in Patients With Elevated Intraocular Pressure https://ClinicalTrials.gov/show/NCT01731002 Completed Aerie Pharmaceuticals 2013-05-31
NCT01722604 Therapeutic Equivalence Study of Generic Brinzolamide vs Azopt https://ClinicalTrials.gov/show/NCT01722604 Completed Bausch Health Americas, Inc. 2012-09-30
NCT01707381 BOL-303259-X With Timolol 0.5% in Subjects With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01707381 Completed Bausch & Lomb Incorporated 2013-12-31
NCT01699464 A Study Assessing the Safety and Ocular Hypotensive Efficacy of AR-12286 in Patients With Elevated Intraocular Pressure for 3 Months https://ClinicalTrials.gov/show/NCT01699464 Completed Aerie Pharmaceuticals 2013-04-30
NCT01693315 Multiple Dose-escalation Study of AMA0076 in Patients With Ocular Hypertension or Primary Open-angle Glaucoma https://ClinicalTrials.gov/show/NCT01693315 Completed Amakem, NV 2013-07-31
NCT01687426 Study Evaluating the Safety and Intraocular Pressure (IOP) Lowering Response of Brimonidine Tartrate Ophthalmic Solution in Subjects With Open Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01687426 Completed Eye Therapies, LLC 2012-12-31
NCT01670266 Single and Multiple Dose Escalation and Two-sequence Crossover Study of ONO-9054 in Patients With Ocular Hypertension or Mild Open-angle Glaucoma https://ClinicalTrials.gov/show/NCT01670266 Completed Ono Pharmaceutical Co. Ltd 2013-05-31
NCT01668524 ATS907 Ph2a Open-Label Dose-ranging Safety and Tolerability in Primary Open Angle Glaucoma (POAG) and Ocular Hypertension (OHT) Subjects https://ClinicalTrials.gov/show/NCT01668524 Completed Altheos, Inc. 2012-08-31
NCT01664039 An Efficacy and Tolerability Study of TRAVATAN® Versus LUMIGAN® https://ClinicalTrials.gov/show/NCT01664039 Completed Alcon Research 2014-06-30
NCT01658839 Pharmacokinetic and Safety Study of Travoprost 0.004% in Pediatric Glaucoma Patients https://ClinicalTrials.gov/show/NCT01658839 Completed Alcon Research 2013-07-31
NCT01655758 24-hour Control of Intraocular Pressure (IOP) in Ocular Hypertension https://ClinicalTrials.gov/show/NCT01655758 Completed University of Parma 2003-12-31
NCT01654484 A Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Patients With POAG or OHT https://ClinicalTrials.gov/show/NCT01654484 Completed Santen Inc. 2012-11-30
NCT01652664 Study of Travoprost Ophthalmic Solution, 0.004% Compared to Timolol (0.5% or 0.25%) in Pediatric Glaucoma Patients https://ClinicalTrials.gov/show/NCT01652664 Completed Alcon Research 2014-03-31
NCT01594970 A Safety and Efficacy Study of Bimatoprost 0.01% in Primary Open-Angle Glaucoma (POAG) or Ocular Hypertension (OH) https://ClinicalTrials.gov/show/NCT01594970 Completed Allergan 2013-01-31
NCT01547598 Safety and Efficacy of LUMIGAN® RC Versus DuoTrav® in Patients Who Require Further Intraocular Pressure (IOP) Reduction https://ClinicalTrials.gov/show/NCT01547598 Completed Allergan 2013-07-31
NCT01528787 Study of AR-13324 in Patients With Elevated Intraocular Pressure https://ClinicalTrials.gov/show/NCT01528787 Completed Aerie Pharmaceuticals 2012-07-31
NCT01528111 Study to Evaluate the Safety, Tolerability, and Efficacy of LX7101 in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01528111 Completed Lexicon Pharmaceuticals 2012-06-30
NCT01525173 A Safety and Efficacy Study of ALPHAGAN® P and LUMIGAN® in Subjects Previously Treated With Latanoprost for Glaucoma and Ocular Hypertension https://ClinicalTrials.gov/show/NCT01525173 Completed Allergan 2012-10-31
NCT01510145 Efficacy of Changing to TRAVATAN® From Prior Therapy https://ClinicalTrials.gov/show/NCT01510145 Completed Alcon Research 2013-05-31
NCT01493427 Efficacy of Changing to TRAVATAN® From Prior Therapy https://ClinicalTrials.gov/show/NCT01493427 Completed Alcon Research 2013-02-28
NCT01493271 A Study of RO5093151 in Patients With Ocular Hypertension Or Open Angle Glaucoma https://ClinicalTrials.gov/show/NCT01493271 Completed Hoffmann-La Roche 2012-11-30
NCT01491867 Continuous Intraocular Pressure (IOP) Measurement and Ability to Detect Treatment Effect https://ClinicalTrials.gov/show/NCT01491867 Completed Semmelweis University 2012-10-31
NCT01481077 A Dose Evaluation Study of the Effect of Plug Placement on the Efficacy and Safety of the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open-Angle Glaucoma https://ClinicalTrials.gov/show/NCT01481077 Completed Mati Therapeutics Inc. 2012-09-30
NCT01481051 A Dose Evaluation Study for the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open-Angle Glaucoma https://ClinicalTrials.gov/show/NCT01481051 Completed Mati Therapeutics Inc. 2012-09-30
NCT01474135 AR-12286 Fixed Dose Combination to Lower Elevated Intraocular Pressure https://ClinicalTrials.gov/show/NCT01474135 Completed Aerie Pharmaceuticals 2012-04-30
NCT01471158 Patient Preference Comparison of AZARGA Versus COSOPT in Patients With Glaucoma https://ClinicalTrials.gov/show/NCT01471158 Completed Alcon Research 2011-05-31
NCT01464424 Assessment of Intraocular Pressure (IOP) Control in Subjects With Open-Angle Glaucoma or Ocular Hypertension Treated With Travoprost 0.004% (TRAVATAN® Z) or Bimatoprost 0.01% (LUMIGAN®) https://ClinicalTrials.gov/show/NCT01464424 Completed Alcon Research 2012-06-30
NCT01453855 Travoprost 3-Month Safety and Efficacy Study https://ClinicalTrials.gov/show/NCT01453855 Completed Alcon Research 2012-08-31
NCT01443988 Subjects With Open-angle Glaucoma, Pseudoexfoliative Glaucoma, or Ocular Hypertension Naïve to Medical and Surgical Therapy, Treated With Two Trabecular Micro-bypass Stents (iStent)or Travoprost https://ClinicalTrials.gov/show/NCT01443988 Completed Glaukos Corporation 2017-01-31
NCT01426867 A Comfort Study of Brinzolamide 1% / Brimonidine 0.2% Fixed Combination, Brinzolamide 1% and Brimonidine 0.2% https://ClinicalTrials.gov/show/NCT01426867 Completed Alcon Research 2011-11-30
NCT01415401 Efficacy and Tolerability of AZARGA® as Replacement Therapy in Patients on COMBIGAN® Therapy in Canada https://ClinicalTrials.gov/show/NCT01415401 Completed Alcon Research 2013-06-30
NCT01410188 Safety/Efficacy Study: OPA-6566 Ophthalmic Solution in Subjects With Primary Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01410188 Completed Kubota Vision Inc. 2012-10-31
NCT01379144 A Study Comparing The Efficacy, Safety And Tolerability Of Latanoprost 75, 100 And 125 ug/ml To Xalatan In The Treatment Of Primary Open-Angle Glaucoma And Ocular Hypertension https://ClinicalTrials.gov/show/NCT01379144 Completed Pfizer 2003-03-31
NCT01369771 The Effects of Preservative-free Prostaglandin Eye Drops in Sign and Symptoms on the Eyes of Patients With Glaucoma https://ClinicalTrials.gov/show/NCT01369771 Completed FinnMedi Oy 2012-06-30
NCT01357616 Fixed Combination Brinzolamide 1%/Timolol 0.5% Versus Brinzolamide 1% + Timolol 0.5% in Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01357616 Completed Alcon Research 2013-01-31
NCT01343082 DE-111 Ophthalmic Solution in Patients With Open Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01343082 Completed Santen Pharmaceutical Co., Ltd. 2013-03-31
NCT01342094 DE-111 Against Timolol Ophthalmic Solution 0.5% https://ClinicalTrials.gov/show/NCT01342094 Completed Santen Pharmaceutical Co., Ltd. 2012-09-30
NCT01342081 DE-111 Against Tafluprost Ophthalmic Solution 0.0015% Alone and Concomitant Use of Tafluprost Ophthalmic Solution 0.0015% Plus Timolol Ophthalmic Solution 0.5% https://ClinicalTrials.gov/show/NCT01342081 Completed Santen Pharmaceutical Co., Ltd. 2012-09-30
NCT01340014 Patient Preference Comparison of AZARGA Versus COSOPT https://ClinicalTrials.gov/show/NCT01340014 Completed Alcon Research 2012-10-31
NCT01336569 Safety and Efficacy of Changing to DuoTrav in Patients Uncontrolled on Timolol https://ClinicalTrials.gov/show/NCT01336569 Completed Alcon Research 2012-03-31
NCT01330979 24-hour Efficacy of AR-12286 https://ClinicalTrials.gov/show/NCT01330979 Completed Aerie Pharmaceuticals 2012-08-31
NCT01327599 Efficacy of Changing to DUOTRAV® From Prior Therapy https://ClinicalTrials.gov/show/NCT01327599 Completed Alcon Research 2012-11-30
NCT04285580 A Study Evaluating the 24-Hour Intraocular Pressure Lowering Effect of Bimatoprost SR in Patients With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT04285580 Recruiting Allergan 2021-03-12
NCT04448223 A Clinical Study to Evaluate the Efficacy and Safety of CKD-351 https://ClinicalTrials.gov/show/NCT04448223 Recruiting Chong Kun Dang Pharmaceutical 2022-12-05
NCT04445519 Phase 3 Trial of NCX 470 vs. Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT04445519 Recruiting Nicox Ophthalmics, Inc. 2021-12-31
NCT04433702 Effect of Negative Pressure on Pattern Electroretinography Readings https://ClinicalTrials.gov/show/NCT04433702 Recruiting Vance Thompson Vision 2020-12-31
NCT04405245 Study to Assess the Efficacy, Safety and Tolerability of AKB-9778 Ophthalmic Solution as and Adjunct to Latanoprost in Patients With Ocular Hypotension or Open Angle Glaucoma https://ClinicalTrials.gov/show/NCT04405245 Recruiting Aerpio Therapeutics 2020-12-31
NCT04335825 Surgical and Refractive Outcomes of Combined Glaucoma Surgery https://ClinicalTrials.gov/show/NCT04335825 Completed Medical University of Bialystok 2019-01-01
NCT04284514 Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AKB-9778 Ophthalmic Solution https://ClinicalTrials.gov/show/NCT04284514 Completed Aerpio Therapeutics 2019-12-15
NCT04202562 Efficacy and Safety of ab Interno Trabeculectomy With the Kahook Dual Blade https://ClinicalTrials.gov/show/NCT04202562 Completed Hospital San Carlos, Madrid 2017-11-29
NCT04149899 Safety and IOP-Lowering Effects of WB007 https://ClinicalTrials.gov/show/NCT04149899 Recruiting Whitecap Biosciences, LLC 2020-06-30
NCT04133311 A Phase III Multinational Multicenter Investigator-Masked Randomised Active-Controlled Trial Comparing the Efficacy and Safety of DE-130A With Xalatan® in Patients With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT04133311 Recruiting Santen SAS 2020-12-31
NCT04061044 A Study to Evaluate the Long Term Safety of OTX-TP (Sustained Release Travoprost) Intracanalicular Insert https://ClinicalTrials.gov/show/NCT04061044 Active, not recruiting Ocular Therapeutix, Inc. 2020-02-29
NCT04035239 Retinal Effects of Balance Goggles System in Glaucoma Balance Goggles System (BGS) in Patients With Glaucoma https://ClinicalTrials.gov/show/NCT04035239 Recruiting Stanford University 2020-02-28
NCT04024072 To Compare the Safety and Efficacy of Perrigo’s Product to an FDA Approved Product for the Treatment of Glaucoma or Ocular Hypertension in Both Eyes https://ClinicalTrials.gov/show/NCT04024072 Active, not recruiting Perrigo Company 2020-02-26
NCT04005079 Pilocarpine After Combined Cataract/Trabectome Surgery https://ClinicalTrials.gov/show/NCT04005079 Recruiting Montefiore Medical Center 2022-07-31
NCT03978546 Diagnostic Performance of Smart Supra Perimetry (The DPSSP Study) https://ClinicalTrials.gov/show/NCT03978546 Recruiting Manchester University NHS Foundation Trust 2020-05-31
NCT03931317 Study Comparing the Effects of Latanoprostene Bunod and Timolol on Retinal Blood Vessel Density and Visual Acuity https://ClinicalTrials.gov/show/NCT03931317 Recruiting University of California, San Diego 2020-12-31
NCT03926975 The Effect of a Scleral Lens on the Anterior Chamber Depth and Minimum Rim Width https://ClinicalTrials.gov/show/NCT03926975 Completed University of Houston 2019-06-15
NCT03901781 Study of ST266 Given by Intranasal Delivery in Glaucoma Suspect Subjects https://ClinicalTrials.gov/show/NCT03901781 Recruiting Noveome Biotherapeutics, formerly Stemnion 2020-12-01
NCT03896633 Therapeutic Equivalence Study of Generic Brinzolamide vs Azopt https://ClinicalTrials.gov/show/NCT03896633 Completed Bausch Health Americas, Inc. 2018-11-17
NCT03891446 Long-term Safety and Efficacy Extension Trial of Bimatoprost SR https://ClinicalTrials.gov/show/NCT03891446 Recruiting Allergan 2024-01-21
NCT03868124 Clinical Study Comparing Two Models of a Travoprost Intraocular Implant https://ClinicalTrials.gov/show/NCT03868124 Recruiting Glaukos Corporation 2021-06-30
NCT03858894 Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution Once Daily and Twice Daily in Subjects With Primary Open-Angle Glaucoma SPECTRUM 6 https://ClinicalTrials.gov/show/NCT03858894 Completed Santen Inc. 2019-06-20
NCT03850782 Evaluation of the Duration of Effect of Bimatoprost SR in Participants With Open-angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT03850782 Recruiting Allergan 2023-07-17
NCT03844945 Efficacy and Systemic Safety of Netarsudil 0.01%, 0.02%, 0.04% Relative to Placebo in Subjects With Open-angle Glaucoma or Ocular Hypertension in Japan https://ClinicalTrials.gov/show/NCT03844945 Completed Aerie Pharmaceuticals 2019-09-19
NCT03808688 Study of Rhopressa® for the Reduction of Elevated Intraocular Pressure in Patients With Glaucoma or Ocular Hypertension in a Real-world Setting https://ClinicalTrials.gov/show/NCT03808688 Completed Aerie Pharmaceuticals 2019-07-26
NCT03798223 Optimal Treatment Protocol for Selective Laser Trabeculoplasty https://ClinicalTrials.gov/show/NCT03798223 Enrolling by invitation Vastra Gotaland Region 2024-01-31
NCT03697811 DE-117 Spectrum 5 Study https://ClinicalTrials.gov/show/NCT03697811 Recruiting Santen Inc. 2020-12-31
NCT03691662 A Phase III Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Glaucoma or Ocular Hypertension - Spectrum 4 Study https://ClinicalTrials.gov/show/NCT03691662 Active, not recruiting Santen Inc. 2019-12-31
NCT03691649 A Phase III Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Glaucoma or Ocular Hypertension - Spectrum 3 Study https://ClinicalTrials.gov/show/NCT03691649 Active, not recruiting Santen Inc. 2019-12-31
NCT03534882 Effects of Prostaglandin Analogue Washout Following Long-term Therapy in Adults With Primary Open Angle Glaucoma https://ClinicalTrials.gov/show/NCT03534882 Completed Western University, Canada 2017-06-22
NCT03529591 Is the Reduction in IOP After Treatment of 180 Degrees Equivalent to Treatment of 360 Degrees With SLT? https://ClinicalTrials.gov/show/NCT03529591 Recruiting Western University, Canada 2020-07-30
NCT03519386 Randomized Study Comparing Two Models of a Travoprost Intraocular Implant to Timolol Maleate Ophthalmic Solution, 0.5% https://ClinicalTrials.gov/show/NCT03519386 Recruiting Glaukos Corporation 2021-06-30
NCT03450629 Evaluation of Safety and Efficacy of Brimonidine Tartrate Ophthalmic Suspension https://ClinicalTrials.gov/show/NCT03450629 Recruiting Sun Pharma Advanced Research Company Limited 2020-12-29
NCT03419975 A Multi-center, Randomized, Blinded Evaluator, Active Control, Parallel, Phase III Study to Evaluate the Efficacy and Safety of TJO-002 in POAG or Ocular Hypertension Patients https://ClinicalTrials.gov/show/NCT03419975 Completed Taejoon Pharmaceutical Co., Ltd. 2017-12-28
NCT01263444 Safety and Efficacy of Adding AZARGA® Adjunctive to Prostaglandin Therapy https://ClinicalTrials.gov/show/NCT01263444 Completed Alcon Research 2013-04-30
NCT01254604 Preservative-Free Tafluprost (MK-2452) for the Treatment of Open-Angle Glaucoma or Ocular Hypertension (MK-2452-002) https://ClinicalTrials.gov/show/NCT01254604 Completed Merck Sharp & Dohme Corp. 2013-05-09
NCT01254370 Safety and Efficacy Study of Catioprost® (Unpreserved Latanoprost 0.005% Emulsion) Compared to Travatan Z® to Treat Glaucoma and Ocular Surface Disease https://ClinicalTrials.gov/show/NCT01254370 Completed Santen SAS 2011-06-30
NCT01253902 Ocular Surface Tolerability Study of Prostaglandin Analogues in Patients With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01253902 Completed Allergan 2011-10-31
NCT01241240 Safety and Efficacy of Triple Combination Therapy in Patients With Primary Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01241240 Completed Allergan 2013-09-30
NCT01241175 The Effect of Intravenous Magnesium Sulfate on Intraocular Pressure Following Tracheal Intubation https://ClinicalTrials.gov/show/NCT01241175 Completed Shiraz University of Medical Sciences NA
NCT01229982 A Study Evaluating the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open-Angle Glaucoma https://ClinicalTrials.gov/show/NCT01229982 Completed Mati Therapeutics Inc. 2011-08-31
NCT01229462 Safety and Efficacy of Brimonidine Tartrate/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01229462 Completed Allergan 2011-09-30
NCT01227291 SYL040012. Tolerance and Effect on Intraocular Pressure in Subjects With Intraocular Pressure (IOP) >= 21 mm Hg https://ClinicalTrials.gov/show/NCT01227291 Completed Sylentis, S.A. 2012-03-31
NCT01223378 Study Comparing the Safety and Efficacy of BOL-303259-X to Latanoprost in Subjects With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01223378 Completed Bausch & Lomb Incorporated 2011-12-20
NCT01217606 Safety and Efficacy of Triple Combination Therapy in Patients With Primary Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01217606 Completed Allergan 2014-09-30
NCT01216943 Safety and Efficacy of Triple Combination Therapy in Patients With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01216943 Completed Allergan 2012-08-31
NCT01215786 Safety and Pharmacodynamics Study of AGN-207281 Ophthalmic Solutions Compared With Timolol Ophthalmic Solution or Placebo in Patients With Ocular Hypertension or Primary Open-Angle Glaucoma https://ClinicalTrials.gov/show/NCT01215786 Completed Allergan 2010-12-31
NCT01177098 Safety and Efficacy of a New Formulation of Bimatoprost/Timolol Ophthalmic Solution Compared With Bimatoprost/Timolol Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01177098 Completed Allergan 2012-02-29
NCT01173471 A Phase IIa Study to Assess the Tolerability, Safety, and Efficacy of AZD4017 for Raised Intra-ocular Pressure https://ClinicalTrials.gov/show/NCT01173471 Completed AstraZeneca 2012-11-30
NCT01170884 Comparing Safety and Efficacy of Combigan® and Lumigan® With Lumigan® Alone in Glaucoma or Ocular Hypertension Subjects Treated With Xalatan® https://ClinicalTrials.gov/show/NCT01170884 Completed Allergan 2010-09-30
NCT01168414 A Study of Ganfort Versus Duotrav in Patients With Primary Open Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01168414 Completed Ministry of Health, Malaysia 2011-01-31
NCT01162603 Latanoprost Versus Tafluprost: 24-hour Intraocular Pressure (IOP) https://ClinicalTrials.gov/show/NCT01162603 Completed Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia 2012-04-30
NCT01157364 Safety and Efficacy of a New Ophthalmic Formulation of Bimatoprost in Patients With Open Angle Glaucoma and Ocular Hypertension https://ClinicalTrials.gov/show/NCT01157364 Completed Allergan 2016-07-27
NCT01126203 Randomized Prospective Study of Selective Laser Trabeculoplasty (SLT) Versus Argon Trabeculoplasty (ALT) in Patients With Pseudoexfoliation Glaucoma and Ocular Hypertension https://ClinicalTrials.gov/show/NCT01126203 Completed University of Calgary 2009-09-30
NCT01123785 A Dose-Escalation Study Designed to Evaluate the Tolerability, Safety, Pharmacokinetics (PK), and Efficacy of Chronic Topical Ocular Application of INO-8875 in Adults With Ocular Hypertension or Primary Open-Angle Glaucoma https://ClinicalTrials.gov/show/NCT01123785 Completed Inotek Pharmaceuticals Corporation 2011-12-31
NCT01114893 Travoprost Five Day Posology Study https://ClinicalTrials.gov/show/NCT01114893 Completed Alcon Research 2010-05-31
NCT01111890 Comparison of the Efficacy of AZARGA® Versus COSOPT® in Patients With Open-Angled Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01111890 Completed Alcon Research 2011-07-31
NCT01110499 Safety and Efficacy of AGN-210961 Ophthalmic Solution Compared With Bimatoprost Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01110499 Completed Allergan 2011-05-31
NCT01099774 Safety and Efficacy of Different Formulations of Bimatoprost Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01099774 Completed Allergan 2011-04-29
NCT01068964 Safety and Efficacy of Bimatoprost Timolol Ophthalmic Solution in Patients With Open Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01068964 Completed Allergan 2010-09-01
NCT01062971 Clinical Study of A Fixed Combination of Timolol-Brimonidine-Dorzolamide https://ClinicalTrials.gov/show/NCT01062971 Completed Laboratorios Sophia S.A de C.V. 2007-08-31
NCT01060579 Study of AR-12286 Versus Latanoprost in Patients With Elevated Intraocular Pressure https://ClinicalTrials.gov/show/NCT01060579 Completed Aerie Pharmaceuticals 2010-08-31
NCT01037036 A Study of the L-PPDS With Adjunctive Xalatan® Eye Drops in Subjects With OH or OAG https://ClinicalTrials.gov/show/NCT01037036 Completed Mati Therapeutics Inc. 2010-04-30
NCT01033422 Safety and Efficacy of Daily CF101 Administered Orally in Subjects With Elevated Intraocular Pressure https://ClinicalTrials.gov/show/NCT01033422 Completed Can-Fite BioPharma 2016-12-31
NCT01028664 Use of an Ocular Telemetry Sensor in Diamox Treated Patients https://ClinicalTrials.gov/show/NCT01028664 Completed Sensimed AG 2010-10-31
NCT01026831 Preservative-Free MK2452 (Tafluprost) for Open-Angle Glaucoma/Ocular Hypertension (MK2452-001)(COMPLETED) https://ClinicalTrials.gov/show/NCT01026831 Completed Merck Sharp & Dohme Corp. 2010-09-17
NCT01001195 Safety and Efficacy of Three Formulations of AGN-210669 Ophthalmic Solution Compared With Bimatoprost Ophthalmic Solution https://ClinicalTrials.gov/show/NCT01001195 Completed Allergan 2010-04-30
NCT00990743 Tolerance and Effect on Intraocular Pressure After Administration of SYL040012 https://ClinicalTrials.gov/show/NCT00990743 Completed Sylentis, S.A. 2010-06-30
NCT00972426 A Study to Evaluate Efficacy and Safety Effects Using Mikelan® LA Ophthalmic Solution (OS) 2% Versus Timoptol® XE Ophthalmic Solution (OS) 0.5% in Ocular Hypertension Patients https://ClinicalTrials.gov/show/NCT00972426 Completed Taiwan Otsuka Pharm. Co., Ltd 2010-08-31
NCT00967811 A Study of Different Formulations of the L-PPDS in Subjects With OH or OAG https://ClinicalTrials.gov/show/NCT00967811 Completed Mati Therapeutics Inc. 2010-05-31
NCT00947661 Efficacy and Safety of SPARC0912 and Reference0912 in Open Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00947661 Completed Sun Pharma Advanced Research Company Limited 2012-05-31
NCT00945958 Evaluation of Safety of SPARC0913 in Open Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00945958 Completed Sun Pharma Advanced Research Company Limited 2012-06-30
NCT00941525 Central Corneal Thickness and 24-hour Fluctuation of Intraocular Pressure https://ClinicalTrials.gov/show/NCT00941525 Completed Aristotle University Of Thessaloniki 2014-07-31
NCT00941096 Intraocular Pressure Reduction With the Bimatoprost/Timolol Fixed Combination https://ClinicalTrials.gov/show/NCT00941096 Completed Larissa University Hospital 2010-11-30
NCT00934089 A Phase 2 Study Of The 24-Hour Intraocular Pressure Lowering And Systemic Exposure Of PF-04217329 https://ClinicalTrials.gov/show/NCT00934089 Completed Pfizer 2010-06-30
NCT00928590 Safety Study of DuoTrav APS in Patients With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00928590 Completed Alcon Research 2010-11-30
NCT00918346 Pharmacodynamics of Tafluprost 0.0015% Eye Drops: a Comparison Between the Preserved and Unpreserved Formulation https://ClinicalTrials.gov/show/NCT00918346 Completed Santen Oy 2006-03-31
NCT00906594 Additive Intra-ocular Pressure Reduction Effect of Fixed Combination of Maleate Timolol 0.5%/Dorzolamide 2% on Monotherapy With Latanoprost in Patients With Elevated Intra-ocular Pressure https://ClinicalTrials.gov/show/NCT00906594 Completed University of Sao Paulo 2008-01-31
NCT03870230 Investigation of Neurovascular Coupling in Glaucoma Patients and Healthy Subjects https://ClinicalTrials.gov/show/NCT03870230 Recruiting Medical University of Vienna 2020-12-31
NCT00902200 A Study of AR-12286 in Patient With Elevated Intraocular Pressure (IOP) https://ClinicalTrials.gov/show/NCT00902200 Completed Aerie Pharmaceuticals 2009-09-30
NCT00892762 Travoprost APS Versus Xalatan® in Patient Reported Outcomes and Ocular Surface Health https://ClinicalTrials.gov/show/NCT00892762 Completed Alcon Research 2011-05-31
NCT00887029 A 12 Week Comparison of DuoTrav and Xalacom in Open-Angle Glaucoma https://ClinicalTrials.gov/show/NCT00887029 Completed Ophthalmic Consultants Centres, Canada 2009-11-30
NCT00878917 Equivalence Study of Dorzolamide 2% Eye Drops Solution https://ClinicalTrials.gov/show/NCT00878917 Completed Alfred E. Tiefenbacher (GmbH & Co. KG) 2010-02-28
NCT00872651 Travoprost 0.004%/Timolol 0.5% Versus Latanoprost 0.005%/Timolol in Chinese Patients With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00872651 Completed Alcon Research 2011-11-30
NCT00868894 Safety and Efficacy Study of DE-104 Ophthalmic Solution to Treat Open-angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00868894 Completed Santen Inc. 2010-05-31
NCT00864838 Oral Acetazolamide, Brimonidine Tartarate, and Anterior Chamber Paracentesis for Ocular Hypertension Control After Intravitreal Bevacizumab https://ClinicalTrials.gov/show/NCT00864838 Completed University of Sao Paulo 2009-02-28
NCT00856622 A Study Demonstrating The Effect Of Latanoprost In Combination With Timolol, Latanoprost Alone And Timolol Alone On Eye Pressure In Open Angle Glaucoma Or Ocular Hypertension In Patients https://ClinicalTrials.gov/show/NCT00856622 Completed Pfizer 1999-06-30
NCT00848536 Efficacy Study of Travoprost APS Versus TRAVATAN https://ClinicalTrials.gov/show/NCT00848536 Completed Alcon Research 2010-01-31
NCT00847483 Comparison of Latanoprost With Travoprost and Bimatoprost in Patients With Elevated IOP. A 12-Weeks, Masked Evaluator, Phase IV Multi-Center Study in the US https://ClinicalTrials.gov/show/NCT00847483 Completed Pfizer 2002-08-31
NCT00846989 Efficacy, Tolerability and Safety of RKI983 (0.05% & 0.10%) vs Xalatan in Patients With POAG or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00846989 Completed Novartis 2009-04-30
NCT00845299 Study of the Effects of Artificial Tears on the Response to the Latanoprost Punctal Plug Delivery System in Subjects With Ocular Hypertension or Open-Angle Glaucoma https://ClinicalTrials.gov/show/NCT00845299 Completed Mati Therapeutics Inc. 2009-12-31
NCT00838721 Evaluation of Pascal Laser Trabeculoplaty https://ClinicalTrials.gov/show/NCT00838721 Completed Santa Clara Valley Health & Hospital System 2010-03-31
NCT04360174 CLN-0045: Safety, and Efficacy of OTX-TIC in Participants With Open Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT04360174 Recruiting Ocular Therapeutix, Inc. 2020-10-31
NCT02136940 Multiple Dose-parallel-group Study of AMA0076 in Patients With Primary Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT02136940 Completed Amakem, NV 2014-11-30
NCT01087671 Ocular Signs and Symptoms in Glaucoma Patients Switched From Latanoprost to Preservative Free Tafluprost Eye Drops https://ClinicalTrials.gov/show/NCT01087671 Completed Santen Oy 2010-10-31
NCT01016691 Safety and Efficacy of a Drug Delivery System in Glaucoma https://ClinicalTrials.gov/show/NCT01016691 Completed Vistakon Pharmaceuticals 2010-02-28
NCT00828906 DuoTrav® Eye Drops As Replacement Therapy Program https://ClinicalTrials.gov/show/NCT00828906 Completed Alcon Research 2009-11-30
NCT00825396 An Open-Label Study of an Ophthalmic Solution to Reduce Intraocular Pressure in Patients With Ocular Hypertension https://ClinicalTrials.gov/show/NCT00825396 Completed Chakshu Research, Inc. 2009-04-30
NCT00824720 Safety and Efficacy of a Glaucoma Drug Delivery System https://ClinicalTrials.gov/show/NCT00824720 Completed Vistakon Pharmaceuticals 2009-04-30
NCT00822081 Comparison of the Fixed Combinations of Brimonidine/Timolol and Dorzolamide/Timolol in Subjects With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00822081 Completed Bp Consulting, Inc 2006-04-30
NCT00822055 Comparison of the Fixed Combinations of Brimonidine/Timolol and Dorzolamide/Timolol in Subjects With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00822055 Completed Allergan 2006-11-30
NCT03960866 Safety and Efficacy of Ophthalmic Phentolamine Mesylate in Glaucoma https://ClinicalTrials.gov/show/NCT03960866 Completed Ocuphire Pharma, Inc. 2019-09-11
NCT02003534 A Study of 0.15% Brimonidine Tartrate in Patients With Primary Open Angle Glaucoma and Ocular Hypertension https://ClinicalTrials.gov/show/NCT02003534 Completed Allergan 2013-02-28
NCT00811564 An Evaluation of the Fixed Combination Brimonidine Tartrate 0.2%/ Timolol Maleate 0.5% to Latanoprost 0.005% in Glaucoma or Ocular Hypertension Subjects https://ClinicalTrials.gov/show/NCT00811564 Completed Allergan 2010-01-31
NCT00809848 Safety and Efficacy of AGN 210669 Ophthalmic Solution in Patients With Ocular Hypertension or Primary Open-Angle Glaucoma https://ClinicalTrials.gov/show/NCT00809848 Completed Allergan 2009-05-31
NCT02003547 A Single Centre Study to Evaluate 3 Ophthalmic Formulations in Healthy Subjects https://ClinicalTrials.gov/show/NCT02003547 Completed Amakem, NV 2013-12-31
NCT01943721 A Study of the VISION5 Product in Patients With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01943721 Completed ForSight Vision5, Inc. 2014-06-30
NCT01896180 Study to Compare the Safety and Efficacy of ALZ-1101 to Latanoprost in Patients With Intraocular Pressure Inadequately Controlled by Latanoprost https://ClinicalTrials.gov/show/NCT01896180 Completed Alleanza Pharmaceuticals, Inc. 2014-01-31
NCT00804648 Patient Satisfaction With Timolol in Subjects With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00804648 Completed Vistakon Pharmaceuticals 2008-12-31
NCT02914509 OTX-16-002: A Phase 3 Study Evaluating the Safety and Efficacy of OTX-TP in Subjects With Open-Angle Glaucoma and Ocular Hypertension https://ClinicalTrials.gov/show/NCT02914509 Completed Ocular Therapeutix, Inc. 2019-03-30
NCT02371746 Safety and Efficacy of ENV515 Travoprost Extended Release (XR) in Patients With Bilateral Ocular Hypertension or Primary Open Angle Glaucoma https://ClinicalTrials.gov/show/NCT02371746 Completed Envisia Therapeutics 2019-02-13
NCT02325518 Comparison of Intraocular Pressure (IOP)-Lowering Efficacy and Safety of AZORGA® Ophthalmic Suspension and COSOPT® Ophthalmic Solution https://ClinicalTrials.gov/show/NCT02325518 Completed Alcon Research 2015-12-31
NCT00781300 Intraocular Pressure With Loteprednol and Dexamethasone https://ClinicalTrials.gov/show/NCT00781300 Completed Federal University of São Paulo 2006-11-30
NCT00763061 Travatan Versus Timoptic in Treating Open-angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00763061 Completed Alcon Research 2008-04-30
NCT00761995 Safety and Efficacy of Brinzolamide Dosed TID With Dorzolamide Dosed TID in Reducing Intraocular Pressure in Patients With Open Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00761995 Completed Alcon Research 2010-07-31
NCT00761709 Safety and Intraocular Pressure (IOP)-Lowering Efficacy of AL-39256 in Patients With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00761709 Completed Alcon Research 2009-10-31
NCT00761319 Phase III Clinical Trial of TRAVATAN Z in Ocular Surface Health https://ClinicalTrials.gov/show/NCT00761319 Completed Alcon Research 2009-09-30
NCT00760539 Safety and Efficacy of Travoprost/Timolol BAC-free https://ClinicalTrials.gov/show/NCT00760539 Completed Alcon Research 2008-12-31
NCT00759239 Phase IV Randomised Double-masked Clinical Trial: Assessing Morning Versus Evening Dosing of a Fixed Dose Combination of Travoprost 0.004% / Timolol Maleate 0.5% in Patients With Primary Open-angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00759239 Completed Alcon Research 2011-01-31
NCT00753168 Phase 1-2 Evaluation of OT-730 Eye Drops in Reducing the Intraocular Pressure in Patients With Ocular Hypertension or Open-Angle Glaucoma https://ClinicalTrials.gov/show/NCT00753168 Completed Othera Pharmaceuticals 2008-12-31
NCT00751127 A 6 Month Study Comparing Latanoprost With Timolol in Patients With Open Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00751127 Completed Pfizer 1994-02-28
NCT00751062 A Study of Open Angle Glaucoma or Ocular Hypertension in Patients Within Scandinavia https://ClinicalTrials.gov/show/NCT00751062 Completed Pfizer 1993-12-31
NCT00751049 A Study of Open Angle Glaucoma or Ocular Hypertension in Patients Within the United Kingdom https://ClinicalTrials.gov/show/NCT00751049 Completed Pfizer 1993-12-31
NCT00708422 Effects of Travatan Z and Xalatan on Ocular Surface Health https://ClinicalTrials.gov/show/NCT00708422 Completed Alcon Research 2009-08-31
NCT00706927 Effect of Xalacom® (Latanoprost/Timolol) and Combigan® (Brimonidine/Timolol) Fixed Combination on Intraocular Pressure and Ocular Blood Flow in Patients With Primary Open Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00706927 Completed Medical University of Vienna 2010-08-31
NCT00698945 Comparison of Istalolâ„¢ 0.5% QD (Timolol Maleate/Sorbitol Complex, ISTA Pharmaceutical) to Brimonidine Tartrate 0.1% BID as Adjunctive Therapy to Latanoprost 0.005% in Adults With Ocular Hypertension (OHT) or Open-Angle Glaucoma (OAG) https://ClinicalTrials.gov/show/NCT00698945 Completed Bp Consulting, Inc 2008-11-30
NCT00691717 Anecortave Acetate Safety in Patients With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00691717 Completed Alcon Research 2009-09-30
NCT00690794 Travatan Z in Ocular Surface Health in Patients With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00690794 Completed Alcon Research 2009-05-31
NCT00683501 Safety, Efficacy, and Pharmacokinetic Profile of DNB-001 in Subjects With Elevated Intraocular Pressure https://ClinicalTrials.gov/show/NCT00683501 Completed Danube Pharmaceuticals, Inc. 2008-08-31
NCT00675207 Comparison of Brimonidine Purite, Dorzolamide, and Brinzolamide as Adjunctive Therapy to Prostaglandin Analogs https://ClinicalTrials.gov/show/NCT00675207 Completed Northwestern Ophthalmic Institute S.C. 2007-07-31
NCT00672997 A Phase III Study of Travoprost/Timolol Combination in Patients With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00672997 Completed Alcon Research 2008-12-31
NCT00670033 Travoprost New Formulations in Patients With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00670033 Completed Alcon Research 2008-09-30
NCT00657579 Safety and Efficacy Study of DE-104 Ophthalmic Solution to Treat Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00657579 Completed Santen Pharmaceutical Co., Ltd. NA
NCT00656240 To Investigate the Safety and Efficacy of DE-104 Ophthalmic Solution to Treat Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00656240 Completed Santen Pharmaceutical Co., Ltd. NA
NCT00652496 Safety and Efficacy Study of Different Formulations of Bimatoprost Once-Daily in Patients With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00652496 Completed Allergan 2005-05-31
NCT00652483 Safety and Efficacy Study of Brimonidine in Patients With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00652483 Completed Allergan 2003-12-31
NCT00652106 Safety and Efficacy Study of Brimonidine/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00652106 Completed Allergan 2004-03-31
NCT00651859 Safety and Efficacy Study of Bimatoprost in Ethnically Japanese Patients With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00651859 Completed Allergan 2004-01-31
NCT00651612 Study to Evaluate Safety of Brimonidine/Timolol Fixed Combination in Glaucoma or Ocular Hypertension Patients https://ClinicalTrials.gov/show/NCT00651612 Completed Allergan 2007-01-31
NCT00650702 Safety and Efficacy of Punctum Plug Delivery System in Subjects With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00650702 Completed Mati Therapeutics Inc. 2009-02-28
NCT00650338 Safety and Efficacy Study of DE-104 Ophthalmic Solution to Treat Open-angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00650338 Completed Santen Inc. 2008-09-30
NCT00821002 A Phase 2 Study of Punctal Placement of the Latanoprost Punctal Plug Delivery System (L-PPDS) https://ClinicalTrials.gov/show/NCT00821002 Completed Mati Therapeutics Inc. 2009-11-30
NCT00647101 A Study to Assess the Efficacy of 3 Months of Latanoprost Treatment in Reducing the Intraocular Pressure in Patients With Ocular Hypertension or Open-Angle Glaucoma https://ClinicalTrials.gov/show/NCT00647101 Completed Pfizer NA
NCT00638742 A Phase 1, Open-Label Study of Latanoprost Acid Plasma Concentrations in Pediatric and Adult Glaucoma Patients Treated With Latanoprost. https://ClinicalTrials.gov/show/NCT00638742 Completed Pfizer 2009-03-31
NCT00637130 Safety and Intraocular Pressure (IOP) Lowering Efficacy of Low Dose Travoprost https://ClinicalTrials.gov/show/NCT00637130 Completed Alcon Research 2008-01-31
NCT00620256 Adjunctive Study of AL-37807 Ophthalmic Suspension https://ClinicalTrials.gov/show/NCT00620256 Completed Alcon Research 2008-07-31
NCT00596791 Ocular Signs and Symptoms in Glaucoma Patients Switched From Latanoprost 0.005% to Preservative Free Tafluprost Eye Drops https://ClinicalTrials.gov/show/NCT00596791 Completed Santen Oy 2008-07-31
NCT00800267 A Study of Glaucoma or Ocular Hypertension in Patients Within the United States https://ClinicalTrials.gov/show/NCT00800267 Completed Pfizer 1999-06-30
NCT00595101 A Phase 2, Dose Finding Study of PF-03187207 in Patients With Primary Open Angle Glaucoma or Ocular Hypertension. https://ClinicalTrials.gov/show/NCT00595101 Completed Bausch & Lomb Incorporated 2008-06-30
NCT00576342 Patient Preference Study https://ClinicalTrials.gov/show/NCT00576342 Completed Alcon Research 2008-01-31
NCT00572455 Safety and Efficacy of PF-04217329 in Patients With Glaucoma or Elevated Eye Pressure. https://ClinicalTrials.gov/show/NCT00572455 Completed Pfizer 2009-06-30
NCT00546286 A Study to Evaluate the Effectiveness of Cosopt® as First Line Therapy (MK-0507A-153) https://ClinicalTrials.gov/show/NCT00546286 Completed Merck Sharp & Dohme Corp. 2007-08-23
NCT00545064 Dry Eye Study With Cosopt® Over 8 Weeks in Patients With Open-Angle Glaucoma or Ocular Hypertension (0507A-152)(COMPLETED) https://ClinicalTrials.gov/show/NCT00545064 Completed Merck Sharp & Dohme Corp. 2008-09-15
NCT00541242 Safety and Efficacy of Bimatoprost Compared With Latanoprost in Patients With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00541242 Completed Allergan 2008-08-31
NCT00539526 Evaluation of Hyperemia With the Use of Ocular Prostaglandin Analogues https://ClinicalTrials.gov/show/NCT00539526 Completed Allergan 2008-07-31
NCT00538304 A Study of the Safety and Efficacy of Bimatoprost in Patients With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00538304 Completed Allergan 2008-05-31
NCT00527592 A Single Dose Comfort Comparison of Travatan Z in One Eye Versus Xalatan in the Opposite Eye in Patients With Primary Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00527592 Completed Alcon Research 2008-08-31
NCT00527501 IOP Lowering Efficacy of Travoprost/Brinzolamide Fixed Combination Ophthalmic Suspension in Patients With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00527501 Completed Alcon Research 2007-12-31
NCT00515424 Tolerability, Safety and Efficacy of RKI983 Eye Drops in Subjects With Primary Open Angle Glaucoma and Ocular Hypertension https://ClinicalTrials.gov/show/NCT00515424 Completed Novartis NA
NCT00508469 Adherence Assessment With Travalert Dosing Aid https://ClinicalTrials.gov/show/NCT00508469 Completed Alcon Research 2010-01-31
NCT00503360 Tolerability, Safety and Efficacy of SAD448 in Subjects With Ocular Hypertension https://ClinicalTrials.gov/show/NCT00503360 Completed Novartis NA
NCT00471380 A Phase IV Study of Travoprost + Brinzolamide to Treat Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00471380 Completed Alcon Research 2008-10-31
NCT00465803 A Phase IIIb Study of DuoTrav to Treat Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00465803 Completed Alcon Research 2009-01-31
NCT00465621 Dose Response Study of AL-37807 Ophthalmic Solution in Patients With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00465621 Completed Alcon Research 2007-07-31
NCT00457795 24-hour IOP-lowering Effect of Brimonidine 0.1% https://ClinicalTrials.gov/show/NCT00457795 Completed Allergan 2009-02-28
NCT00449956 MK0507A Clinical Study in Patients With Glaucoma and Ocular Hypertension (0507A-149)(COMPLETED) https://ClinicalTrials.gov/show/NCT00449956 Completed Merck Sharp & Dohme Corp. 2008-02-16
NCT00443924 Study of INS115644 Ophthalmic Solution in Subjects With Ocular Hypertension or Glaucoma https://ClinicalTrials.gov/show/NCT00443924 Completed Merck Sharp & Dohme Corp. 2009-04-30
NCT00441883 Dose-Finding Study Comparing the Safety and Efficacy of Latanoprost to a Novel Treatment for Glaucoma https://ClinicalTrials.gov/show/NCT00441883 Completed Bausch & Lomb Incorporated 2008-02-29
NCT00440141 Brimonidine 0.1% Versus Brinzolamide 1% as Adjunctive Therapy to Latanoprost 0.005% https://ClinicalTrials.gov/show/NCT00440141 Completed Allergan 2007-03-31
NCT00440011 Bimatoprost 0.03% Versus Travoprost 0.004% in Patients Currently on Latanoprost 0.005% https://ClinicalTrials.gov/show/NCT00440011 Completed Allergan 2007-10-31
NCT00402493 Study to Determine if Taking OTC Non-Steroidal Anti-Inflammatory Affects Eye Pressure in Patients Using Glaucoma Drops https://ClinicalTrials.gov/show/NCT00402493 Completed Philadelphia Eye Associates 2008-03-31
NCT00820300 A Safety Study of the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open Angle Glaucoma https://ClinicalTrials.gov/show/NCT00820300 Completed Mati Therapeutics Inc. 2009-12-31
NCT00383019 A Study Comparing Xalacom And Xalatan In Patients With Primary Open Angle Glaucoma (POAG) Or Ocular Hypertension (OH). https://ClinicalTrials.gov/show/NCT00383019 Completed Pfizer 2007-10-31
NCT00372931 A Phase II Study of AL-37807 to Treat Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00372931 Completed Alcon Research 2007-08-31
NCT00372827 Study of Brinzolamide and Timolol When Added to Travoprost in Primary Open-angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00372827 Completed Alcon Research 2006-01-31
NCT00314171 A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00314171 Completed Alcon Research 2007-08-31
NCT00348062 A Multicenter Evaluation of Methods to Reduce Hyperemia Associated With Bimatoprost Therapy for Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00348062 Completed Innovative Medical NA
NCT00348023 Bimatoprost Monotherapy vs. Dual Therapy With Travoprost and Timolol in Patients With Glaucoma and Ocular Hypertension https://ClinicalTrials.gov/show/NCT00348023 Completed Innovative Medical NA
NCT00333125 A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00333125 Completed Alcon Research 2007-02-28
NCT00332540 Safety and Efficacy Study of Bimatoprost/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00332540 Completed Allergan 2003-08-31
NCT00332436 Safety and Efficacy Study of Brimonidine/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00332436 Completed Allergan 2001-11-30
NCT00332384 Safety and Efficacy Study of Brimonidine/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00332384 Completed Allergan 2001-11-30
NCT00332345 Safety and Efficacy Study of Brimonidine/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00332345 Completed Allergan 1999-08-31
NCT00332072 Safety and Efficacy Study of Bimatoprost/Timolol Fixed Combination in Patients Wtih Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00332072 Completed Allergan 2003-08-31
NCT00332059 Safety and Efficacy Study of Bimatoprost/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00332059 Completed Allergan 2004-09-30
NCT00330577 24-Hour Intraocular Pressure (IOP) And Blood Pressure Control In Glaucoma And Ocular Hypertension Patients https://ClinicalTrials.gov/show/NCT00330577 Completed Aristotle University Of Thessaloniki 2007-04-30
NCT00329095 An Evaluation of Use of Topical Ocular Hypotensive Medication by Compliance https://ClinicalTrials.gov/show/NCT00329095 Completed Robin, Alan L., M.D. NA
NCT00326092 A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00326092 Completed Alcon Research 2006-08-31
NCT00314158 A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00314158 Completed Alcon Research 2007-01-31
NCT00311389 A 12-Month Study to Evaluate the Efficacy and Safety of Once-Daily Instillation of Combination Glaucoma Therapy in Patients With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00311389 Completed Alcon Research 2004-09-30
NCT00304785 Latanoprost Versus Fotil https://ClinicalTrials.gov/show/NCT00304785 Completed Pharmaceutical Research Network NA
NCT00300443 Safety and Efficacy Study of Bimatoprost in Patients With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00300443 Completed Allergan 2007-06-30
NCT00300079 Study of the Intraocular Pressure (IOP)-Lowering Efficacy of Azopt 1.0% Compared to Timolol 0.5% in Patients With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00300079 Completed Alcon Research 2007-09-30
NCT00293800 A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00293800 Completed Alcon Research 2005-12-31
NCT00293787 A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00293787 Completed Alcon Research 2005-08-31
NCT00293761 A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00293761 Completed Alcon Research 2006-05-31
NCT00288951 Phase III Safety and Efficacy Study to Evaluate a Glaucoma Therapy in Open-Angle Glaucoma or Ocular Hypertension Patients https://ClinicalTrials.gov/show/NCT00288951 Completed Alcon Research 2005-06-30
NCT00287521 A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00287521 Completed Alcon Research 2006-02-28
NCT00277498 A 12-week, Randomized, Double-masked, Parallel Group Comparison of Evening Dosing With Xalacom in Subjects With Glaucoma https://ClinicalTrials.gov/show/NCT00277498 Completed Pfizer NA
NCT00273481 Cosopt Versus Xalacom https://ClinicalTrials.gov/show/NCT00273481 Completed Pharmaceutical Research Network NA
NCT00273442 Assessing Cosopt Switch Patients https://ClinicalTrials.gov/show/NCT00273442 Completed Pharmaceutical Research Network NA
NCT00273429 Cosopt Versus Xalatan https://ClinicalTrials.gov/show/NCT00273429 Completed Pharmaceutical Research Network NA
NCT00230763 Determination Of Predictive Factors Allowing To An Additional 10% Reduction Of Intra-Ocular Pressure https://ClinicalTrials.gov/show/NCT00230763 Completed Pfizer 2007-10-31
NCT00798759 Examination of Ocular Surface Effects With Administration of Travatan Z and XALATAN https://ClinicalTrials.gov/show/NCT00798759 Completed Alcon Research 2009-05-31
NCT00168363 Safety and Efficacy of Brimonidine in Patients With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00168363 Completed Allergan 2006-08-31
NCT00159653 A 12-Week, Randomized, Double-Masked, Parallel Group Comparison Of Evening Dosing With Xalacom In Subjects With Glaucoma https://ClinicalTrials.gov/show/NCT00159653 Completed Pfizer 2007-06-30
NCT00143208 Evaluation Of Intraocular Pressure Lowering-Effect Of Xalacom In Patients With Poag Or Oh. https://ClinicalTrials.gov/show/NCT00143208 Completed Pfizer NA
NCT00140062 Efficacy And Safety Of Xalatan Compared To Usual Care In Patients With Open Angle Glaucoma Or Ocular Hypertension. https://ClinicalTrials.gov/show/NCT00140062 Completed Pfizer NA
NCT00140049 A 12week, Randomized, Evaluator-Masked, Parallel Group Comparing Evening Dosing Of Xalacom Vs Cosopt In Subj W/ Glaucoma https://ClinicalTrials.gov/show/NCT00140049 Completed Pfizer NA
NCT00121147 Additivity Study: Additive Effect on Eye Pressure of Azopt and Alphagan P to Travatan https://ClinicalTrials.gov/show/NCT00121147 Completed Hermann Eye Center NA
NCT00108017 Comparison of the Effects of Two Glaucoma Drugs Over 24 Hours (0507A-137)(COMPLETED) https://ClinicalTrials.gov/show/NCT00108017 Completed Merck Sharp & Dohme Corp. 2006-07-31
NCT00069719 Phase II Safety and Efficacy Study to Evaluate a Glaucoma Therapy in Open-Angle Glaucoma or Ocular Hypertension Patients https://ClinicalTrials.gov/show/NCT00069719 Completed Alcon Research 2003-08-31
NCT00069706 Phase II Safety and Efficacy Study to Evaluate a Glaucoma Therapy in Open-angle Glaucoma or Ocular Hypertension Patients https://ClinicalTrials.gov/show/NCT00069706 Completed Alcon Research 2003-10-31
NCT00061542 Safety and Efficacy Study of BETOPTIC S 0.25% and Timolol Gel-forming Solution 0.25% and 0.5% in Pediatric Patients With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00061542 Completed Alcon Research 2006-11-30
NCT00061529 A Phase III Study of Brimonidine Tartrate Ophthalmic Solution, 0.15% in Patients With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00061529 Completed Alcon Research 2004-07-31
NCT00061516 Safety and Efficacy Study of BETAXON 0.5% and AZOPT 1.0% in Pediatric Patients With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00061516 Completed Alcon Research 2006-02-28
NCT00061503 Mechanism of Action of TRAVATAN 0.004% in Subjects With Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00061503 Completed Alcon Research 2004-03-31
NCT00051168 A Long-term Safety Study of Once-daily Travatan https://ClinicalTrials.gov/show/NCT00051168 Completed Alcon Research 2009-03-31
NCT00051155 A 6-Week Safety and Efficacy Study of Travatan Compared to Xalcom in Subjects With Open-Angle Glaucoma(OAG) or Ocular Hypertension(OHT) https://ClinicalTrials.gov/show/NCT00051155 Completed Alcon Research 2004-07-31
NCT00051142 A Safety and Efficacy Study of Travoprost 0.004% Compared to Latanoprost 0.005% in Patients With Open-Angle Glaucoma (OAG) or Ocular Hypertension (OHT) https://ClinicalTrials.gov/show/NCT00051142 Completed Alcon Research 2004-06-30
NCT00047541 Phase 3 Study to Evaluate IOP Lowering Therapy in Open Angle Glaucoma and Ocular Hypertension C-01-70 https://ClinicalTrials.gov/show/NCT00047541 Completed Alcon Research 2003-11-30
NCT00047528 Phase 3 Study to Evaluate IOP Lowering Therapy in Open Angle Glaucoma and Ocular Hypertension C-02-41 https://ClinicalTrials.gov/show/NCT00047528 Completed Alcon Research 2003-11-30
NCT00047515 Phase 3 Study to Evaluate IOP Lowering Therapy in Open Angle Glaucoma and Ocular Hypertension C-01-69 https://ClinicalTrials.gov/show/NCT00047515 Completed Alcon Research 2003-12-31
NCT00047593 Phase 3 Study Comparing IOP Lowering in OAG or OH in Japanese Subjects C-01-98 https://ClinicalTrials.gov/show/NCT00047593 Completed Alcon Research 2004-07-31
NCT00735449 Comparing Efficacy and Safety of Combigan With Timolol Adjunctive to Xalatan in Glaucoma or Ocular Hypertension Subjects https://ClinicalTrials.gov/show/NCT00735449 Completed Allergan 2009-12-31
NCT00799682 Exploratory Study Comparing Signs and Symptoms in Patients With Ocular Hypertension or Glaucoma Using Xalatan R® or Travatan Z® https://ClinicalTrials.gov/show/NCT00799682 Completed Ophthalmic Consultants of Long Island 2011-01-31
NCT00051194 A 6-week Safety & Efficacy Study of Combination Intraocular Pressure-lowering Therapy in Patients With Open-angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00051194 Completed Alcon Research 2003-07-31
NCT00051181 A Safety and Efficacy Study of Travoprost 0.004% Compared to Latanoprost 0.005% in Patients With Chronic Angle-Closure Glaucoma https://ClinicalTrials.gov/show/NCT00051181 Completed Alcon Research 2003-06-30
NCT00150267 A 5-Year Postmarketing Safety Study Of Xalcom In Patients With Open Angle Glaucoma Or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00150267 Completed Pfizer NA
NCT00219596 Xalacom And Combination Of Unfixed Latanoprost And Timolol In Subjects With Open-Angle Glaucoma Or Ocular Hypertension https://ClinicalTrials.gov/show/NCT00219596 Completed Pfizer NA
NCT00000125 Ocular Hypertension Treatment Study (OHTS) https://ClinicalTrials.gov/show/NCT00000125 Completed Washington University School of Medicine 2002-06-30

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03250819 Gene Polymorphisms of Corticosteroid-induced Ocular Hypertension https://ClinicalTrials.gov/show/NCT03250819 Completed Maastricht University Medical Center 2019-02-06
NCT02384772 Survey of Patients Taking IOP-Lowering Eye Drops https://ClinicalTrials.gov/show/NCT02384772 Completed ForSight Vision5, Inc. 2015-05-31
NCT02348476 A Study of Simbrinzaâ„¢ Therapy in Patients With Open-Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT02348476 Completed Allergan 2015-04-30
NCT02165631 The Diurnal and Nocturnal Effect of Simbrinza and Timolol on Intraocular Pressure and Ocular Perfusion Pressure https://ClinicalTrials.gov/show/NCT02165631 Completed University of Colorado, Denver 2016-03-31
NCT01281020 Adherence With Fixed Versus Unfixed Glaucoma Therapy https://ClinicalTrials.gov/show/NCT01281020 Completed Aristotle University Of Thessaloniki 2011-06-30
NCT01999348 A Study of GANFORT® UD in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT) in a Medical Setting https://ClinicalTrials.gov/show/NCT01999348 Completed Allergan 2014-12-19
NCT01987752 Safety and Efficacy of Combigan® Ophthalmic Solution in Korea https://ClinicalTrials.gov/show/NCT01987752 Completed Allergan 2011-11-30
NCT01976624 Safety and Efficacy of Bimatoprost/Timolol (Ganfort®) Ophthalmic Solution in Korea https://ClinicalTrials.gov/show/NCT01976624 Completed Allergan 2014-01-31
NCT01853085 A Study of Patients With Primary Open Angle Glaucoma or Ocular Hypertension Switched to Lumigan® UD Monotherapy for Medical Reasons https://ClinicalTrials.gov/show/NCT01853085 Completed Allergan 2014-03-01
NCT01814761 A Study of Bimatoprost 0.01% in the Clinical Setting https://ClinicalTrials.gov/show/NCT01814761 Completed Allergan 2014-08-31
NCT01779778 Diurnal and Nocturnal Effect of Travatan With SofZia Preservative on Intraocular Pressure and Ocular Perfusion Pressure https://ClinicalTrials.gov/show/NCT01779778 Completed University of Colorado, Denver 2013-04-30
NCT01737853 Comparison of Efficacy & Tolerability Between Ganfort vs Krytantek in Mexican Patients With Primary Open-Angle Glaucoma (POAG) or Ocular Hypertension (OHT) https://ClinicalTrials.gov/show/NCT01737853 Completed Allergan S.A. DE C.V.. 2011-02-28
NCT01735214 An Observational Study of Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT) Who Switched IOP-lowering Treatments https://ClinicalTrials.gov/show/NCT01735214 Completed Allergan 2014-04-10
NCT01646151 A Study Comparing IOP-Lowering Treatments to Bimatoprost in Patients With Primary Open Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01646151 Completed Allergan 2013-04-30
NCT01637246 A Study of Patients With Primary Open Angle Glaucoma or Ocular Hypertension Who Were Insufficiently Responsive to Monotherapy https://ClinicalTrials.gov/show/NCT01637246 Completed Allergan 2011-11-30
NCT01632423 A Study of Lumigan® in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT) https://ClinicalTrials.gov/show/NCT01632423 Completed Allergan 2010-11-30
NCT01628614 A Study of Intraocular Pressure (IOP) Reduction in Newly Diagnosed Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT) https://ClinicalTrials.gov/show/NCT01628614 Completed Allergan 2011-07-31
NCT01628601 GANfort® in Patients With Primary Open Angle Glaucoma or Ocular Hypertension Who Are Insufficiently Responsive to Monotherapy https://ClinicalTrials.gov/show/NCT01628601 Completed Allergan 2011-06-30
NCT01628588 Lumigan® in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT) https://ClinicalTrials.gov/show/NCT01628588 Completed Allergan 2010-12-31
NCT01589510 A Study of Lumigan® 0.01% in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT) https://ClinicalTrials.gov/show/NCT01589510 Completed Allergan 2013-02-28
NCT01568008 Observational Study of Lumigan® 0.01% for Treatment of Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT) https://ClinicalTrials.gov/show/NCT01568008 Completed Allergan 2012-09-30
NCT01489670 Observational Study of Lumigan® 0.01% Treatment for Patients With Primary Open Angle Glaucoma or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01489670 Completed Allergan 2013-03-31
NCT01342419 Circadian Rhythms of Aqueous Humor Dynamics When Using Brimonidine in Humans With Ocular Hypertension https://ClinicalTrials.gov/show/NCT01342419 Completed University of Nebraska 2011-10-31
NCT04036214 Efficacy and Safety Outcomes of Optometrist Performed Selective Laser Trabeculoplasty (SLT) https://ClinicalTrials.gov/show/NCT04036214 Recruiting Northeastern State University 2020-07-31
NCT03927118 Effect of Dexamethasone Implant on Optic Disc https://ClinicalTrials.gov/show/NCT03927118 Completed Bulent Ecevit University 2018-09-01
NCT03584958 Comparing Refractive and Visual Outcomes of MIGS and Traditional Surgeries https://ClinicalTrials.gov/show/NCT03584958 Enrolling by invitation Wills Eye 2021-12-31
NCT01265719 Long-Term Non-Interventional Latanoprost Study https://ClinicalTrials.gov/show/NCT01265719 Completed Pfizer 2016-02-29
NCT01261871 Intraocular Pressure During Robotic Assisted Laparoscopic Procedures Utilizing Steep Trendelenburg Positioning https://ClinicalTrials.gov/show/NCT01261871 Completed United States Naval Medical Center, San Diego 2010-05-31
NCT01210963 Central Corneal Thickness With SENSIMED Triggerfish https://ClinicalTrials.gov/show/NCT01210963 Completed Sensimed AG 2011-02-28
NCT01206361 Real World Data Study Assessing The Persistency Of Xalacom And The Other Fixed Dose Combination Products, Duotrav And Ganfort, In The United Kingdom https://ClinicalTrials.gov/show/NCT01206361 Completed Pfizer 2010-08-31
NCT01191008 Long Term Use Of Xalacom In Patients Glaucoma Or Ocular Hypertension https://ClinicalTrials.gov/show/NCT01191008 Completed Pfizer 2015-05-31
NCT01092273 Bimatoprost Versus Travoprost at Cairo University https://ClinicalTrials.gov/show/NCT01092273 Completed Cairo University NA
NCT01067482 The Performances of Spectral Domain Optical Coherence Tomography (OCT) for Distinguishing Glaucomatous Eyes https://ClinicalTrials.gov/show/NCT01067482 Completed Prince of Songkla University 2010-03-31
NCT01012245 Non-Interventional Study In Patients With Ocular Hypertension And Open Angle Glaucoma Treated With Xalatan And Xalacom https://ClinicalTrials.gov/show/NCT01012245 Completed Pfizer 2008-12-31
NCT00950690 Efficacy and Tolerability of Xalatan in Patients https://ClinicalTrials.gov/show/NCT00950690 Completed Pfizer 2007-12-31
NCT00834171 A Retrospective Evaluation of the Intraocular Pressure Spikes With Loteprednol and Loteprednol/Tobramycin https://ClinicalTrials.gov/show/NCT00834171 Completed Allergan 2009-12-31
NCT00823043 A Comfort Survey of Open-angle Glaucoma or Ocular Hypertension Patients Treated With 2 Drugs https://ClinicalTrials.gov/show/NCT00823043 Completed Vistakon Pharmaceuticals 2009-07-31
NCT01540370 Study Comparing Quantitative Assessments in Open-angle Glaucoma (OAG) and/or Ocular Hypertension (OHT) https://ClinicalTrials.gov/show/NCT01540370 Completed Allergan 2012-07-31
NCT00803998 Ocular Hypertension Treatment Study (OHTS) https://ClinicalTrials.gov/show/NCT00803998 Completed The New York Eye & Ear Infirmary NA
NCT00803387 Dry Eye and Irritation Comparison of Latanoprost With the Preservative Versus Travoprost Without Preservative https://ClinicalTrials.gov/show/NCT00803387 Completed United States Air Force 2008-09-30
NCT00801437 Non Interventional Study With Primary Open Angle Glaucoma and/or Ocular Hypertension Patients Treated With Xalacom® After Failure of Previous Antiglaucoma Therapy. https://ClinicalTrials.gov/show/NCT00801437 Completed Pfizer 2009-06-30
NCT02863224 Advanced Glycation End Products as a Biomarker for Accelerated Ageing https://ClinicalTrials.gov/show/NCT02863224 Completed University of Plymouth 2018-07-31
NCT03972852 Establishment of an Anaesthetic Protocol for Examinations for Children With Glaucoma or Suspected Glaucoma https://ClinicalTrials.gov/show/NCT03972852 Recruiting Johannes Gutenberg University Mainz 2020-06-30
NCT00716742 Safety and Efficacy Study of Bimatoprost, Latanoprost, and Travoprost in Patients With Elevated Intraocular Pressure (IOP) and Open-angle Glaucoma (OAG) https://ClinicalTrials.gov/show/NCT00716742 Completed Allergan 2007-09-30
NCT00691639 Collection of Blood Specimens From Patients in AL-3789 Studies for Elevated Intraocular Pressure (IOP) https://ClinicalTrials.gov/show/NCT00691639 Completed Alcon Research 2009-08-31
NCT00680329 Glaucoma Adherence Study, Spain https://ClinicalTrials.gov/show/NCT00680329 Completed Alcon Research 2009-07-31
NCT00676637 Glaucoma Adherence Study https://ClinicalTrials.gov/show/NCT00676637 Completed Alcon Research 2010-02-28
NCT00621335 A Investigator Masked Parallel Comparison of Tolerability of Combigan and Cosopt https://ClinicalTrials.gov/show/NCT00621335 Completed DBYAN Medicine Professional Corporation 2008-02-29
NCT00494923 Early Diagnosis, Pathogenesis and Progression of Open Angle Glaucoma https://ClinicalTrials.gov/show/NCT00494923 Recruiting University of Erlangen-Nürnberg Medical School 2015-12-31
NCT00486252 Non Interventional Study in Patients With Open Angle Glaucoma and/or Ocular Hypertension Treated With XALATAN® https://ClinicalTrials.gov/show/NCT00486252 Completed Pfizer 2008-01-31
NCT00430209 Neurovascular Coupling in Eyes of Glaucoma Patients https://ClinicalTrials.gov/show/NCT00430209 Completed University Hospital, Basel, Switzerland 2013-12-31
NCT00429819 Neurovascular Coupling in Eyes of Glaucoma Patients https://ClinicalTrials.gov/show/NCT00429819 Completed University Hospital, Basel, Switzerland 2014-06-30
NCT00424996 Utility of Heidelberg Retina Tomograph in Monitoring Glaucoma Progression https://ClinicalTrials.gov/show/NCT00424996 Completed University Health Network, Toronto 2013-12-31
NCT00347191 Relationship Between Central Corneal Thickness and Intraocular Pressure Measures Instruments. https://ClinicalTrials.gov/show/NCT00347191 Completed Aston University NA
NCT00334750 Distribution of Risk Factors in Ocular Hypertension and Open-Angle Glaucoma Patients in Canada https://ClinicalTrials.gov/show/NCT00334750 Completed Pfizer 2009-04-30
NCT00001152 Pigment Dispersion Syndrome With and Without Glaucoma https://ClinicalTrials.gov/show/NCT00001152 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001161 Abnormalities of the Eye’s Anterior Chamber, Iris, Cornea and Lens https://ClinicalTrials.gov/show/NCT00001161 Completed National Institutes of Health Clinical Center (CC) NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT03928665 Long-term Observation of Ophthalmic Changes in Patients With Obstructive Sleep Apnea https://ClinicalTrials.gov/show/NCT03928665 Recruiting Wroclaw Medical University 2022-10-01